The Gut-Brain Protocol

Calm, focused days and restful nights, in two formulas.

Choose your plan

60 stick packs (30 Daily for the morning, 30 Nightly for the evening) · mix one with 8 fl oz of cold or room temperature water

Contains milk. Non-GMO · Gluten free · No caffeine or melatonin.

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One shipment No subscription or renewal

Pre-order · charged when ordered
Estimated to ship January 2027.

Pre-order details

Subscription renewal timing starts from your first shipment. Cancel before shipping for a full refund.

Choose an option to see its exact checkout charge, billing cadence, and renewal terms.

  • 30-day first-order guarantee from delivery
  • Free standard U.S. shipping

Shipping & pre-order terms · Guarantee & returns

Made to look forward to.

The Daily Calm Focus box with a Daily Calm Focus stick pack.
The Nightly Rest and Restore box with a Nightly Rest and Restore stick pack.

Daily Calm Focus: Peach Mango, bright and light for the start of the day. Nightly Rest & Restore: Hibiscus Vanilla, soft and warm for the end of it.

One minute, twice a day.

  1. Open one stick pack.
  2. Add it to 8 fl oz of water.Cold or room temperature.
  3. Stir.
  • MorningStir one serving of Daily Calm Focus into water with your morning.
  • EveningStir one Nightly Rest & Restore stick pack into 8 fl oz of cold or room-temperature water 30 to 60 minutes before bed.

One routine, split across your day.

The same probiotic and the same prebiotic fiber sit in both formulas.

A Daily Calm Focus stick pack

MorningOne Daily Calm Focus stick

A Nightly Rest and Restore stick pack

EveningOne Nightly Rest & Restore stick

Prebiotic just means food for your gut bacteria.

Your gut, supported around the clock.

Bimuno® GOS is the fiber we use, and it feeds the good bacteria already living in your gut. Every serving carries 1.37 g of it, the amount used in the published trial, alongside the DR7 probiotic. Morning and evening both.

Golden powder blooming through water against deep teal
Golden powder blooming through water against deep teal

Five ingredients, and what each one is for.

Both formulas share L. plantarum DR7, a probiotic strain with human trials of its own, and Bimuno GOS, a prebiotic fiber. The research below is on each ingredient. The finished Protocol has not been clinically tested.

A Daily Calm Focus stick pack and a Nightly Rest and Restore stick pack.
L. plantarum DR7Probiotic. A live bacterial strain. 2 billion CFU a day

1 billion CFU per formula, 2 billion a day. Supports a healthy stress response and gut health.

What the study measuredIn a 12-week placebo-controlled study analysing 111 adults, DR7 at 1 billion CFU daily improved reported stress symptoms by week eight. Chong 2019.

Bimuno GOSPrebiotic fiber for beneficial gut bacteria. 2.7 g across both daily servings

1.37 g in every serving, morning and evening. Feeds the good bacteria in your gut for digestive comfort.

What the study measuredIn a placebo-controlled trial, adults taking Bimuno B-GOS providing 1.37 g of GOS daily reported less bloating, gas and abdominal pain after one week. Vulevic 2018.

L-theanineAmino acid, the kind found in green tea. 200 mg

The exact amount studied for calm, focused attention, without caffeine.

What the study measuredPut through a demanding mental task, people who had taken 200 mg of L-theanine stayed physically steadier, with a smaller rise in heart rate. That is the amount in Daily Calm Focus. Kimura 2007.

B VitaminsFive B vitamins, including active-form B6 and B12. 5 vitamins

B1 25 mg, B2 15 mg, B5 50 mg, B6 as P-5-P 10 mg, B12 250 mcg. See the Supplement Facts for each vitamin form.

What the study measuredPooling eight placebo-controlled trials of 28 days or more, people taking vitamins and minerals reported less stress, less fatigue and less confusion than those on placebo. Long and Benton 2013.

Magnesium glycinateAlso called magnesium bisglycinate. 200 mg
elemental

200 mg of elemental magnesium in the evening formula, in a chelated form that is gentle on the stomach.

What the study measured155 adults who were sleeping badly took magnesium in this same bisglycinate form for four weeks, and rated their sleep better than the placebo group did. Schuster 2025 used 250 mg a day. Nightly Rest & Restore carries 200 mg, and the trial did not test the finished formula.

Daily Calm Focus Supplement Facts
Supplement Facts
Serving Size 1 stick pack (3.65 g)
Servings Per Container 30
NutrientAmount Per Serving% Daily Value
Calories10
Total Carbohydrate2 g<1%*
Dietary Fiber1 g4%*
Total Sugars<1 g†
Thiamin (as thiamin hydrochloride)25 mg2,083%
Riboflavin15 mg1,154%
Vitamin B6 (as pyridoxal-5-phosphate)10 mg588%
Vitamin B12 (as methylcobalamin)250 mcg10,417%
Pantothenic acid (as D-calcium pantothenate)50 mg1,000%
Sodium10 mg<1%
Bimuno® Galacto-oligosaccharides (1.37 g GOS)1.83 g†
L-Theanine200 mg†
Lactiplantibacillus plantarum DR770 mg (1 billion CFU)†

* Percent Daily Values are based on a 2,000 calorie diet. † Daily Value not established. Other ingredients: Natural flavors, citric acid, monk fruit extract, and bamboo extract (stem and leaf).

Contains milk.

Nightly Rest & Restore Supplement Facts
Supplement Facts
Serving Size 1 stick pack (6.2 g)
Servings Per Container 30
NutrientAmount Per Serving% Daily Value
Calories10
Total Carbohydrate2 g<1%*
Dietary Fiber1 g4%*
Magnesium (as magnesium bisglycinate)200 mg48%
Sodium10 mg<1%
Bimuno® Galacto-oligosaccharides (1.37 g GOS)1.83 g†
Lactiplantibacillus plantarum DR770 mg (1 billion CFU)†

* Percent Daily Values are based on a 2,000 calorie diet. † Daily Value not established. Other ingredients: Citric acid, natural flavors, bamboo extract (stem and leaf), and monk fruit extract.

Contains milk.

What’s not in it.

No caffeine in the morning formula. No melatonin in the evening formula. No ashwagandha in either.

Non-GMO and gluten free. Contains milk.

Before you order.

When does my order ship?

Pre-order now. Your first delivery ships January 2027, and you are charged today. You can cancel any time before it ships for a full refund. Full terms are in the shipping and pre-order policy.

When will I notice a difference?

Ingredient studies followed different timelines, and individual responses vary. They are not trials of the finished Protocol. Your first-order money-back guarantee lasts 30 days from the day your order is delivered.

Why two formulas?

Daily Calm Focus brings L-theanine and B vitamins to your morning. Nightly Rest & Restore brings magnesium to your evening. Both contain DR7 and Bimuno GOS, so the gut-brain base is the same whichever you choose.

Can I take just one?

Yes. Daily Calm Focus and Nightly Rest & Restore are available separately. Choose the morning formula, the evening formula, or both to suit your routine. Each product page shows its current purchase options.

Are there allergens?

It contains milk, because Bimuno GOS is made from lactose. Both formulas are Non-GMO and gluten free.

Who should check with a clinician first?

If you are pregnant, nursing, taking medication, or managing a medical condition, speak with a qualified clinician before use.

How does the subscription work?

Choose monthly, three-month or six-month billing. The initial payment is taken when you pre-order. First shipment is estimated for January 2027, and renewal timing is counted from that first shipment. Your selected plan shows the recurring charge before you order. Cancel future renewals from your account.

What is the guarantee?

A 30-day money-back guarantee from the day your first order is delivered. See the refund and returns policy.

The Gut-Brain Protocol box on a shelf with a Daily Calm Focus stick pack and a Nightly Rest and Restore stick pack.

Start the Protocol.

Pre-orders are charged today. First shipment is estimated for January 2027.

Choose your plan

30-day first-order guarantee from delivery · cancel future renewals anytime

Contains milk. Individual results vary. Bimuno® is a trademark of Clasado Limited.