Choose your daily protocol.

Take both formulas together, or start with the part of your day that needs support first.

Pre-orders open. Estimated to ship Fall 2026.

Serene Biotics products

The Daily Calm Focus and Nightly Rest and Restore cartons, shipped together as the Gut-Brain Protocol Recommended
Morning + eveningPeach Mango · Hibiscus Vanilla

Gut-Brain Protocol

Both cartons shipped together. 30 morning servings, 30 evening servings, and at least 2.75 g a day of Bimuno® GOS, the fiber your good bacteria live on.

3-month plan $261.60 per delivery
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Daily Calm Focus carton, Peach Mango
MorningPeach Mango

Daily Calm Focus

30 morning servings. L-theanine at the 200 mg used in published trials, with an active B complex. Caffeine-free.

3-month plan $157.47 per delivery
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Nightly Rest and Restore carton, Hibiscus Vanilla
EveningHibiscus Vanilla

Nightly Rest & Restore

30 evening servings. 200 mg of elemental magnesium as fully chelated bisglycinate, the form worth taking before bed. Melatonin-free.

3-month plan $157.47 per delivery
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Compare all three.

Final price, cadence, and due-today terms are confirmed on each product page.

Comparison of Gut-Brain Protocol, Daily Calm Focus, and Nightly Rest & Restore
Compare Gut-Brain Protocol Daily Calm Focus Nightly Rest & Restore
When to use Morning after waking; evening 30-60 minutes before bed After waking, with or without food 30-60 minutes before bed
Servings 60 total: 30 morning, 30 evening 30 morning servings 30 evening servings
Flavor Peach Mango + Hibiscus Vanilla Peach Mango Hibiscus Vanilla
Caffeine / melatonin Caffeine-free morning; melatonin-free evening Caffeine-free Melatonin-free
Plan pricing $261.60per delivery · 3-month plan $157.47per delivery · 3-month plan $157.47per delivery · 3-month plan
Gut-Brain ProtocolBoth formulas
When
Morning after waking; evening 30-60 minutes before bed
Servings
60 total: 30 morning, 30 evening
Flavor
Peach Mango + Hibiscus Vanilla
Plan
$261.60 per delivery, 3-month plan
View plans
Daily Calm FocusMorning
When
After waking, with or without food
Servings
30 morning servings
Flavor
Peach Mango
Plan
$157.47 per delivery, 3-month plan
View plans
Nightly Rest & RestoreEvening
When
30-60 minutes before bed
Servings
30 evening servings
Flavor
Hibiscus Vanilla
Plan
$157.47 per delivery, 3-month plan
View plans