Find your daily ritual.

Choose morning, evening, or the complete Gut-Brain Protocol.

Help me choose

Pre-orders open. Charged when ordered. Estimated to ship January 2027.

Serene Biotics products

The closed Gut-Brain Protocol box on a bright ivory studio surface Recommended
Morning + eveningPeach Mango · Hibiscus Vanilla

Gut-Brain Protocol

The whole day covered: calm focus in the morning, restful sleep at night, and your gut looked after by both. 60 stick packs (30 morning, 30 evening).

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One-time price $110Monthly subscription $99/moSave 10%
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The Daily Calm Focus box.
MorningPeach Mango

Daily Calm Focus

For calm, focused mornings, without caffeine. L-theanine for focus that holds, five B vitamins to help turn food into energy, and a clinically studied probiotic and prebiotic pair for your gut. 30 mornings a box.

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One-time price $70Monthly subscription $63/moSave 10%
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The Nightly Rest and Restore box.
EveningHibiscus Vanilla

Nightly Rest & Restore

For restful nights, without melatonin. Magnesium glycinate provides 200 mg of elemental magnesium, with DR7 probiotic and Bimuno GOS prebiotic. 30 evenings a box.

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One-time price $70Monthly subscription $63/moSave 10%
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Monthly subscriptions renew monthly. Savings compared with one-time purchase.

How you can check.

  • TodayWhat is in each formula, how much, and the study behind it, on the ingredients page.
  • Before it shipsEvery production lot has to clear independent Eurofins testing for identity, label accuracy, heavy metals and microbial contaminants.
  • After releaseLot-level Certificates of Analysis open here, looked up by the code on your box.

Compare all three.

Final price, cadence, and due-today terms are confirmed on each product page.

Comparison of Gut-Brain Protocol, Daily Calm Focus, and Nightly Rest & Restore
Compare Gut-Brain Protocol Daily Calm Focus Nightly Rest & Restore
When to use Morning after waking; evening 30-60 minutes before bed After waking 30-60 minutes before bed
Servings 60 stick packs (30 morning, 30 evening) 30 morning servings 30 evening servings
Flavor Peach Mango + Hibiscus Vanilla Peach Mango Hibiscus Vanilla
Caffeine / melatonin Caffeine-free morning; melatonin-free evening Caffeine-free Melatonin-free
Plan pricing
Subscribe & save
One-time price $110Monthly subscription $99/moSave 10%
Subscribe & save
One-time price $70Monthly subscription $63/moSave 10%
Subscribe & save
One-time price $70Monthly subscription $63/moSave 10%
Gut-Brain ProtocolBoth formulas
When
Morning after waking; evening 30-60 minutes before bed
Servings
60 stick packs (30 morning, 30 evening)
Flavor
Peach Mango + Hibiscus Vanilla
Plan
Subscribe & save
One-time price $110Monthly subscription $99/moSave 10%
View plans
Daily Calm FocusMorning
When
After waking
Servings
30 morning servings
Flavor
Peach Mango
Plan
Subscribe & save
One-time price $70Monthly subscription $63/moSave 10%
View plans
Nightly Rest & RestoreEvening
When
30-60 minutes before bed
Servings
30 evening servings
Flavor
Hibiscus Vanilla
Plan
Subscribe & save
One-time price $70Monthly subscription $63/moSave 10%
View plans